Diuretics are drugs that increase the volume of urine produced by promoting the excretion of salt and water from the kidneys. There are several types of diuretics, each working in a distinct way.
Thiazide diuretics inhibit sodium re-absorption at the beginning of the distal convoluted tubules. Potassium sparing diuretics prevent excessive loss of potassium at the distal convoluted tubules.
A combination of a potassium sparing diuretic with a thiazide diuretic is used to reduce edema due to salt and water retention in disorders of the heart, kidneys, liver or lungs. They are used commonly in treatment of hypertension.
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Source:drugs.com
Amiloride Hcl
Amiloride is usually used in combination with other diuretics ('water pills') to treat high blood pressure and heart failure in patients who have low amounts of potassium in their bodies or for whom low potassium levels in the body could be dangerous. Amiloride is in a class of medications called diuretics. It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine, but reduces the loss of potassium.
The combination of amiloride and hydrochlorothiazide is used alone or in combination with other medications to treat high blood pressure and heart failure in patients who have low amounts of potassium in their bodies or for whom low potassium levels in the body could be dangerous. Amiloride and hydrochlorothiazide are in a class of medications called diuretics ('water pills'). They work by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
The combination of triamterene and hydrochlorothiazide is used to treat high blood pressure and edema (fluid retention; excess fluid held in body tissues) in patients who have lower amounts of potassium in their bodies or for whom low potassium levels in the body could be dangerous. The combination of triamterene and hydrochlorothiazide is in a class of medications called diuretics ('water pills'). They work by causing the kidneys to get rid of unneeded water and salt from the body into the urine.